LINCOLN, Neb. (COLOGNE) – A University of Nebraska-Lincoln research team received $25,000 from a challenge issued by the National Institutes of Health.
The challenge was to use advanced gene editing techniques using innovative solutions to deliver genome editors into cells. The research team's solution was to use natural nanoparticles found in milk to transport the gene editor anywhere in the body.
Programmable nanoparticles are different from traditional nanoparticles. They can evade immune system cells that destroy foreign substances. This technology will revolutionize the world of disease treatment.
“Many of the diseases today, and in general, in recent times, are caused by genetic diseases caused by mutations, so this technology will help us understand the fundamentals known to humanity,” said UNL Professor of Molecular Nutrition Janos Zempleni. “It will be possible to treat all diseases in the near future.”
The way the technology works is that researchers attach three peptides from the membrane to each nanoparticle. They all perform different tasks and help gene editing techniques reach the right location intact.
There are still two phases to this challenge, and in the second phase, the team will present data from a study demonstrating the technology's delivery and editing performance. The winner of this phrase will not be announced until April 2025.
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